Article
Association between KIR genes and dust mite sensitization in a Brazilian population.
Human immunology - 1 Jan 2018
Caniatti Marcela Caleffi da Costa Lima, Borelli Sueli Donizete, Guilherme Ana Lúcia Falavigna, Franzener Soraya Barrionuevo, Tsuneto Luiza Tamie
Abstract excerpt
BACKGROUND: Killer cell immunoglobulin-like receptors (KIRs), found on the surface of natural killer (NK) cells, play a key role in controlling the innate response. Such response depends on a series of cellular interactions between these receptors and HLA activating/inhibiting ligands. Atopic diseases have been associated with genes that regulate cytokine production and HLA genes, which may either protect or...
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