Article
HLA-DRB1*07 may have a susceptibility and DRB1*04 a protective effect upon the development of a sensitization to house dust mite Dermatophagoides pteronyssinus.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jan 2001
Kim Y K, Oh H B, Oh S Y, Cho S H, Kim Y Y, Min K U
Abstract excerpt
BACKGROUND: IgE responses to house dust mite-derived allergens seem to be the most important in the development of atopic asthma and rhinitis, but it has been difficult to demonstrate genetic control of the IgE response to the allergens. OBJECTIVE: This study was undertaken to investigate the association between sensitization to house dust mite, D. pteronyssinus (DP), and genotypes of HLA-DRB1 alleles. METHODS:...
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