Article
Association of KIR Genes and MHC Class I Ligands with Atopic Dermatitis.
Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 2021
Margolis David J, Mitra Nandita, Hoffstad Ole J, Kim Brian S, Monos Dimitri S, Phillips Elizabeth J
Abstract excerpt
Atopic dermatitis (AD) is a chronic illness that is associated with immune dysregulation. NK cell function has previously been associated with AD. NK cells directly interact with polymorphic HLA class I ligand variants using killer cell Ig-like receptors (KIRs). The purpose of this study was to identify potential associations between NK cell function and AD by evaluating variation in the presence of KIR genes as...
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