Article
Emerging role for the killer-cell immunoglobulin-like receptors genotype, in the susceptibility of skin diseases.
Journal of dermatological science - 1 Jul 2013
Matusiak Łukasz, Białynicki-Birula Rafał, Szepietowski Jacek C
Abstract excerpt
NK cells are a major group of immune cells responsible for the phenomenon of natural, innate cytotoxicity. One of the better studied receptors of human NK cells are killer cell immunoglobulin-like receptors (KIR) responsible for checking the presence of MHC class I molecules, which serve as their ligands. Although previously treated as specific for NK cells, nowadays these receptors are known to also occur on T...
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