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Article

HLA-DRB108:03:02 and HLA-DQB106:01:01 are associated with house dust mite-sensitive allergic rhinitis in Chinese subjects.

International forum of allergy & rhinology - 1 Aug 2016

Zhao Yanming, Zhao Yali, Li Jingyun, Zhang Yuan, Zhang Luo

Abstract excerpt

BACKGROUND: Allergic rhinitis (AR) is a multifactorial immunologic disease that is influenced by both genetic and environment factors. House dust mites (HDMs) are important inhalant aeroallergens and are an epidemiologic risk factor for AR. Similarly, the human leukocyte antigen (HLA) class II genes DQB1 and DRB1 have been shown to be associated with AR and play an important role in the regulation of the immune...

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PMID: 27013183
DOI: 10.1002/alr.21747

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