Article
Immunogenetics of atopic asthma: association of DRB1*1101 DQA1*0501 DQB1*0301 haplotype with Dermatophagoides spp.-sensitive asthma in a sample of the Venezuelan population.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jan 1999
Lara-Marquez M L, Yunis J J, Layrisse Z, Ortega F, Carvallo-Gil E, Montagnani S, Makhatadze N J, Pocino M, Granja C, Yunis E
Abstract excerpt
BACKGROUND: Genes linked to the major histocompatibility complex (MHC), have been implicated in atopic asthma. Asthma is highly prevalent in the Venezuelan population (estimated at 20%) and genetic markers are needed to identify populations at risk and plan intervention strategies. OBJECTIVE: To study the influence of the MHC class I and class II genes in the susceptibility to atopic asthma. METHODS: MHC-class I...
Topics
- Adolescent
- Adult
- Alleles
- Antigens, Dermatophagoides
- Asthma
- Child
- Child, Preschool
- Family Health
- Female
- Gene Frequency