Article
An Exhaustive Scan Method for SNP Main Effects and SNP × SNP Interactions Over Highly Homozygous Genomes.
Journal of computational biology : a journal of computational molecular cell biology - 1 Dec 2017
Tsai Shin-Fu, Tung Chih-Wei, Tsai Chen-An, Liao Chen-Tuo
Abstract excerpt
Genome-wide association studies (GWAS) have been a powerful tool for exploring potential relationships between single-nucleotide polymorphisms (SNPs) and biological traits. For screening out important genetic variants, it is desired to perform an exhaustive scan over a whole genome. However, this is usually a challenging and daunting task in computation, due mainly to the large number of SNPs in GWAS. In this...
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