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Article

Quick approximation of threshold values for genome-wide association studies.

Briefings in bioinformatics - 27 Nov 2019

Hao Zhiyu, Jiang Li, Gao Jin, Ye Jinhua, Zhao Jingli, Li Shuling, Yang Runqing

Abstract excerpt

Standard normal statistics, chi-squared statistics, Student's t statistics and F statistics are used to map quantitative trait nucleotides for both small and large sample sizes. In genome-wide association studies (GWASs) of single-nucleotide polymorphisms (SNPs), the statistical distributions depend on both genetic effects and SNPs but are independent of SNPs under the null hypothesis of no genetic effects....

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PMID: 30219836
DOI: 10.1093/bib/bby082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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