Article
In silico phenotypic screening method of mutants based on statistical modeling of genetically mixed samples.
Journal of bioinformatics and computational biology - 1 Dec 2005
Kaminuma Eli, Heida Naohiko, Yoshizumi Takeshi, Nakazawa Miki, Matsui Minami, Toyoda Tetsuro
Abstract excerpt
In comprehensive functional genomics projects, systematic analysis of phenotypes is vital. However, conventional phenotypic screening is done mainly by imprecise visual observation of qualitative traits, and, therefore, in silico screening techniques for quantitative traits are required. In this report, we propose in silico phenotypic screening method that utilizes a Gaussian mixture model for the trait...
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