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Article

Detection of Mycobacterium tuberculosis pncA Mutations by the Nipro Genoscholar PZA-TB II Assay Compared to Conventional Sequencing.

Antimicrobial agents and chemotherapy - 1 Jan 2018

Willby Melisa J, Wijkander Maria, Havumaki Joshua, Johnson Kartee, Werngren Jim, Hoffner Sven, Denkinger Claudia M, Posey James E

Abstract excerpt

Pyrazinamide (PZA) is a standard component of first-line treatment regimens for Mycobacterium tuberculosis and is included in treatment regimens for drug-resistant M. tuberculosis whenever possible. Therefore, it is imperative that susceptibility to PZA be assessed reliably prior to the initiation of therapy. Currently available growth-based PZA susceptibility tests are time-consuming, and results can be...

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Identifiers

PMID: 29084743
DOI: 10.1128/AAC.01871-17
PMCID: PMC5740318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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