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Pyrazinamide Susceptibility and pncA Mutation Profiles of Mycobacterium tuberculosis among Multidrug-Resistant Tuberculosis Patients in Bangladesh.

Antimicrobial agents and chemotherapy - 1 Sept 2017

Rahman Arfatur, Ferdous Sara Sabrina, Ahmed Shahriar, Rahman S M Mazidur, Uddin Mohammad Khaja Mafij, Pholwat Suporn, Gratz Jean, Houpt Eric, Banu Sayera

Abstract excerpt

Pyrazinamide (PZA) is a frontline antituberculosis (anti-TB) drug used in both first- and second-line treatment regimens. However, due to complex laboratory requirements, the PZA susceptibility test is rarely performed, leading to a scarcity of data on susceptibility to PZA. Bangladesh is a country with a burden of high rates of both TB and multidrug-resistant TB (MDR-TB), but to our knowledge, published data on...

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Amidohydrolases
Antitubercular Agents
Bangladesh
Drug Resistance, Multiple, Bacterial
Microbial Sensitivity Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mycobacterium tuberculosis

Tuberculosis, Multidrug-Resistant

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Identifiers

PMID: 28630193
DOI: 10.1128/AAC.00511-17
PMCID: PMC5571327

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