Article
Mutational and epigenetic signatures in cancer tissue linked to environmental exposures and lifestyle.
Current opinion in oncology - 1 Jan 2018
Perduca Vittorio, Omichessan Hanane, Baglietto Laura, Severi Gianluca
Abstract excerpt
PURPOSE OF REVIEW: In this article, we describe how recent advances in the study of mutational and epigenetic signatures in tumours provide new opportunities to understand the role of the environment and lifestyle in cancer development. RECENT FINDINGS: Cancer-related mutational events have been investigated for decades but only recently the wide availability of genomic sequences and epigenomic data from...
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