Article
Epigenetic mechanisms and cancer: An interface between the environment and the genome
17 Jun 2011
Abstract excerpt
Although epidemiological studies support the role of environment in a wide range of human cancers, the precise mechanisms by which environmental exposures promote cancer development and progression remain poorly understood. Environmental factors have been proposed to promote the development of malignancies by eliciting epigenetic changes; however, it is only with recent advances in epigenetics and epigenomics...
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