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Article

Cancer susceptibility: epigenetic manifestation of environmental exposures.

Cancer journal (Sudbury, Mass.) - 1 Jan 2000

Weidman Jennifer R, Dolinoy Dana C, Murphy Susan K, Jirtle Randy L

Abstract excerpt

Cancer is a disease that results from both genetic and epigenetic changes. Discordant phenotypes and varying incidences of complex diseases such as cancer in monozygotic twins as well as genetically identical laboratory animals have long been attributed to differences in environmental exposures. Accumulating evidence indicates, however, that disparities in gene expression resulting from variable modifications in...

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PMID: 17464241
DOI: 10.1097/PPO.0b013e31803c71f2

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