Article
Genetic variants of glucose metabolism and exposure to smoking in African American breast cancer.
Endocrine-related cancer - 1 Apr 2023
Jung Su Yon, Papp Jeanette C, Sobel Eric M, Pellegrini Matteo, Yu Herbert
Abstract excerpt
Insulin resistance (IR) is a well-established risk factor for breast cancer (BC) development in African American (AA) postmenopausal women. While obesity and IR are more prevalent in AA than in white women, they are under-represented in genome-wide studies for systemic regulation of IR. By examining 780 genome-wide IR single-nucleotide polymorphisms (SNPs) available in our data, we tested 4689 AA women in a...
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