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Article

Effect of genetic variants and traits related to glucose metabolism and their interaction with obesity on breast and colorectal cancer risk among postmenopausal women.

BMC cancer - 26 Apr 2017

Jung Su Yon, Sobel Eric M, Papp Jeanette C, Zhang Zuo-Feng

Abstract excerpt

BACKGROUND: Impaired glucose metabolism-related genetic variants and traits likely interact with obesity and related lifestyle factors, influencing postmenopausal breast and colorectal cancer (CRC), but their interconnected pathways are not fully understood. By stratifying via obesity and lifestyles, we partitioned the total effect of glucose metabolism genetic variants on cancer risk into two putative...

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Blood Glucose
Breast Neoplasms
Colorectal Neoplasms
Genome-Wide Association Study
Insulin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insulin Resistance

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PMID: 28446149
DOI: 10.1186/s12885-017-3284-7
PMCID: PMC5405540

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DGKB
GCKR

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