Article
Telomere length in poor-risk chronic lymphocytic leukemia: associations with disease characteristics and outcome.
Leukemia & lymphoma - 1 Jul 2018
Steinbrecher Daniela, Jebaraj Billy Michael Chelliah, Schneider Christof, Edelmann Jennifer, Cymbalista Florence, Leblond Véronique, Delmer Alain, Ibach Stefan, Tausch Eugen, Scheffold Annika, Bloehdorn Johannes, Hallek Michael, Dreger Peter, Döhner Hartmut, Stilgenbauer Stephan
Abstract excerpt
Telomere length in chronic lymphocytic leukemia (CLL) is described as an independent prognostic factor based largely on previously untreated patients from chemotherapy based trials. Here, we studied telomere length associations in high-risk, relapsed/refractory CLL treated with alemtuzumab in the CLL2O study (n = 110) of German and French CLL study groups. Telomere length (median 3.28 kb, range 2.52-7.24 kb) was...
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