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Telomere-Driven Checkpoint Remodeling Is Associated with Cytogenetic Risk in Chronic Lymphocytic Leukemia

2026-01-26

Abstract excerpt

Chronic lymphocytic leukemia (CLL) exhibits marked clinical heterogeneity that is closely associated with genomic instability. Although cytogenetic abnormalities are widely used for risk stratification, they do not fully capture the biological complexity of the disease. Telomere dysfunction and alterations in DNA damage response pathways have been implicated in disease progression, but their relationship with cyto...

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Literature Corpus work
03ad3b43-4f07-5438-81b4-fac7097ca447
DOI
10.20944/preprints202601.1904.v1
Open publication

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Telomere-Driven Checkpoint Remodeling Is Associated with Cytogenetic Risk in Chronic Lymphocytic LeukemiaDOI 10.20944/preprints202601.1904.v1
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