Article
Telomeres and prognosis in patients with chronic lymphocytic leukaemia.
International journal of hematology - 1 Jan 2011
Sellmann Ludger, de Beer Dirk, Bartels Marius, Opalka Bertram, Nückel Holger, Dührsen Ulrich, Dürig Jan, Seifert Marc, Siemer Dörte, Küppers Ralf, Baerlocher Gabriela M, Röth Alexander
Abstract excerpt
In the present study, telomere length, telomerase activity, the mutation load of immunoglobulin variable heavy chain (IGHV) genes, and established prognostic factors were investigated in 78 patients with chronic lymphocytic leukaemia (CLL) to determine the impact of telomere biology on the pathog...
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