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Article

Telomere length and telomerase levels delineate subgroups of B-cell chronic lymphocytic leukemia with different biological characteristics and clinical outcomes.

Haematologica - 1 Jan 2012

Rampazzo Enrica, Bonaldi Laura, Trentin Livio, Visco Carlo, Keppel Sonia, Giunco Silvia, Frezzato Federica, Facco Monica, Novella Elisabetta, Giaretta Ilaria, Del Bianco Paola, Semenzato Gianpietro, De Rossi Anita

Abstract excerpt

BACKGROUND: B-cell chronic lymphocytic leukemia is a clinically heterogeneous disease; some patients rapidly progress and die within a few years of diagnosis, whereas others have a long life expectancy with minimal or no treatment. Telomere length and telomerase levels have been proposed as prognostic factors; however, very few cases have been characterized for both parameters and no study has analyzed the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21933855
DOI: 10.3324/haematol.2011.049874
PMCID: PMC3248931

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