Article
A Rare Variant (rs933717) at FBXO31-MAP1LC3B in Chinese Is Associated With Systemic Lupus Erythematosus.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Feb 2018
Qi Yuan-Yuan, Zhou Xu-Jie, Nath Swapan K, Sun Celi, Wang Yan-Na, Hou Ping, Mu Rong, Li Chun, Guo Jian-Ping, Li Zhan-Guo, Wang Geng, Xu Hu-Ji, Hao Yan-Jie, Zhang Zhuo-Li, Yue Wei-Hua, Zhang Huoru, Zhao Ming-Hui, Zhang Hong
Abstract excerpt
OBJECTIVE: Recent evidence from genetic, cell biology, and animal model studies has suggested a pivotal role of autophagy in mediating systemic lupus erythematosus (SLE). However, the genetic basis has not yet been thoroughly examined. Therefore, the aim of the present study was to identify additional susceptibility variants in autophagy-related genes along with their functional significance. METHODS: First, we...
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