Article
Gene-gene interaction of ATG5, ATG7, BLK and BANK1 in systemic lupus erythematosus.
International journal of rheumatic diseases - 1 Dec 2016
Dang Jie, Li Jiangxia, Xin Qian, Shan Shan, Bian Xianli, Yuan Qianqian, Liu Na, Ma Xiaochun, Li Yan, Liu Qiji
Abstract excerpt
AIM: Autophagy-related gene 5 (ATG5), ATG7, B-lymphoid tyrosine kinase (BLK) and B-cell scaffold protein with ankyrin repeats 1 (BANK1) are involved in B-cell signaling; several genome-wide association studies detected these genes as candidates involved in systemic lupus erythematosus (SLE). We aimed to replicate the association of these genes with SLE in Chinese Han and to search for possible gene-gene...
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