Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr.

Proceedings of the National Academy of Sciences of the United States of America - 31 Oct 2017

Zakany Jozsef, Darbellay Fabrice, Mascrez Bénédicte, Necsulea Anamaria, Duboule Denis

Abstract excerpt

During embryonic development, Hox genes participate in the building of a functional digestive system in metazoans, and genetic conditions involving these genes lead to important, sometimes lethal, growth retardation. Recently, this phenotype was obtained after deletion of Haglr, the Hoxd antisense growth-associated long noncoding RNA (lncRNA) located between Hoxd1 and Hoxd3 In this study, we have analyzed the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to CRISPR-Cas Systems

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Genes, Homeobox

Share to Homeodomain Proteins

Share to RNA, Long Noncoding

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 29042517
DOI: 10.1073/pnas.1712511114
PMCID: PMC5676926

Genes

HOXD10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr.PMID 29042517Read ↗

Loss of the epithelial transcription factor grhl3 leads to variably penetrant developmental phenotypes in zebrafish.Semantic proximity Read ↗

Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations.Semantic proximity Read ↗

The mother superior mutation ablates foxd3 activity in neural crest progenitor cells and depletes neural crest derivatives in zebrafish.Semantic proximity Read ↗

Defective cranial skeletal development, larval lethality and haploinsufficiency in Myod mutant zebrafish.Semantic proximity Read ↗

Long bone development requires a threshold of Hox function.Semantic proximity Read ↗

The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle.Semantic proximity Read ↗

Defects and rescue of the minor salivary glands in Eda pathway mutants.Semantic proximity Read ↗

Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish.Semantic proximity Read ↗

Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy.Semantic proximity Read ↗

Function of posterior HoxD genes in the morphogenesis of the anal sphincter.Semantic proximity Read ↗

Reduced body growth and excessive incisor length in insertional mutants mapping to mouse Chromosome 13.Semantic proximity Read ↗

Hoxd and Gli3 interactions modulate digit number in the amniote limb.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.