Article
APOL1 nephropathy risk variants do not associate with subclinical atherosclerosis or left ventricular mass in middle-aged black adults.
Kidney international - 1 Mar 2018
Gutiérrez Orlando M, Limou Sophie, Lin Feng, Peralta Carmen A, Kramer Holly J, Carr J Jeffrey, Bibbins-Domingo Kirsten, Winkler Cheryl A, Lewis Cora E, Kopp Jeffrey B
Abstract excerpt
Prior studies reported associations of APOL1 nephropathy risk variants with subclinical atherosclerosis. However, these findings were limited to older individuals with high comorbidities. To evaluate this in younger individuals, we calculated associations of APOL1 risk variants (high risk [2 risk variants] vs. low risk [0-1 risk variant]) with prevalent, incident, or progressive coronary artery calcification, a...
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