Article
Kit W-sh Mutation Prevents Cancellous Bone Loss during Calcium Deprivation.
Calcified tissue international - 1 Jan 2018
Lotinun Sutada, Suwanwela Jaijam, Poolthong Suchit, Baron Roland
Abstract excerpt
Calcium is essential for normal bone growth and development. Inadequate calcium intake increases the risk of osteoporosis and fractures. Kit ligand/c-Kit signaling plays an important role in regulating bone homeostasis. Mice with c-Kit mutations are osteopenic. The present study aimed to investigate whether impairment of or reduction in c-Kit signaling affects bone turnover during calcium deprivation....
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