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Article

Genomic analysis of Isometamidium Chloride resistance in Trypanosoma congolense.

International journal for parasitology. Drugs and drug resistance - 1 Dec 2017

Tihon Eliane, Imamura Hideo, Van den Broeck Frederik, Vermeiren Lieve, Dujardin Jean-Claude, Van Den Abbeele Jan

Abstract excerpt

Isometamidium Chloride (ISM) is one of the principal drugs used to counteract Trypanosoma congolense infection in livestock, both as a prophylactic as well as a curative treatment. However, numerous cases of ISM resistance have been reported in different African regions, representing a significant constraint in the battle against Animal African Trypanosomiasis. In order to identify genetic signatures associated...

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Identifiers

PMID: 29032180
DOI: 10.1016/j.ijpddr.2017.10.002
PMCID: PMC5645165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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