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Unravelling drug resistance in leishmaniasis: genomic adaptations and emerging therapies

26 May 2025

Abstract excerpt

Leishmaniasis remains a significant global health challenge, with over a billion people at risk of infection and limited effective treatment options due to escalating drug resistance. This review explores the underlying mechanisms of drug resistance in Leishmania species, focusing on genomic plasticity as a driving factor for survival and adaptation. Key mechanisms, including genetic mutations, gene...

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PMID: 40492115
DOI: 10.3389/fmolb.2025.1573618

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