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Article

A Compendium of Co-regulated Protein Complexes in Breast Cancer Reveals Collateral Loss Events.

Cell systems - 25 Oct 2017

Ryan Colm J, Kennedy Susan, Bajrami Ilirjana, Matallanas David, Lord Christopher J

Abstract excerpt

Protein complexes are responsible for the bulk of activities within the cell, but how their behavior and abundance varies across tumors remains poorly understood. By combining proteomic profiles of breast tumors with a large-scale protein-protein interaction network, we have identified a set of 285 high-confidence protein complexes whose subunits have highly correlated protein abundance across tumor samples. We...

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Identifiers

PMID: 29032073
DOI: 10.1016/j.cels.2017.09.011
PMCID: PMC5660599

Genes

CDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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