Article

Loss of long-range co-expression is a common feature in cancer

2022-10-28

Abstract excerpt

Cancer cells display common features and enabling characteristics collectively known as the Hallmarks of Cancer, which occur alongside alterations in the regulatory mechanisms controlling gene transcription. Gene co-expression networks (GCNs) provide a framework to identify correlated gene sets that may share these regulatory mechanisms. Previously, we reported the loss of long-range co-expression in breast, lung,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 487e5404-268d-5ad7-af6b-d4d79d0c18c2
DOI: 10.1101/2022.10.27.513947

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Loss of long-range co-expression is a common feature in cancerDOI 10.1101/2022.10.27.513947Read

Loss of long-range co-expression is a common trait in cancerSemantic proximity Read

Loss of Long Distance Co-Expression in Lung CancerSemantic proximity Read

The network structure of hematopoietic cancersSemantic proximity Read

Disruption of metazoan gene regulatory networks in cancer alters the balance of co-expression between genes of unicellular and multicellular originsSemantic proximity Read

Shared regulation and functional relevance of local gene co-expression revealed by single cell analysisSemantic proximity Read

Gene co-expression analysis for functional classification and gene-disease predictions.Semantic proximity Read

Patient-Specific Analysis of Co-expression Networks for Predicting Clinical Outcomes in Breast CancerSemantic proximity Read

CoRegNet: Unraveling Gene Co-regulation Networks from Public RNA-Seq Repositories Using a Beta-Binomial Statistical ModelSemantic proximity Read

The molecular basis, genetic control and pleiotropic effects of local gene co-expressionSemantic proximity Read

Patient-specific gene co-expression networks reveal novel subtypes and predictive biomarkers in lung adenocarcinomaSemantic proximity Read

Elucidating gene expression patterns across multiple biological contexts through a large-scale investigation of transcriptomic datasetsSemantic proximity Read

Communication Breakdown and Evolution of the Cancer CellSemantic proximity Read