Article
Gene expression correlations in human cancer cell lines define molecular interaction networks for epithelial phenotype.
PloS one - 1 Jan 2014
Kohn Kurt W, Zeeberg Barry M, Reinhold William C, Pommier Yves
Abstract excerpt
Using gene expression data to enhance our knowledge of control networks relevant to cancer biology and therapy is a challenging but urgent task. Based on the premise that genes that are expressed together in a variety of cell types are likely to functions together, we derived mutually correlated genes that function together in various processes in epithelial-like tumor cells. Expression-correlated genes were...
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