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Article

Time-on-Task Effect During Sleep Deprivation in Healthy Young Adults Is Modulated by Dopamine Transporter Genotype.

Sleep - 1 Dec 2017

Satterfield Brieann C, Wisor Jonathan P, Schmidt Michelle A, Van Dongen Hans P A

Abstract excerpt

Study Objectives: The time-on-task (TOT) effect and total sleep deprivation (TSD) have similar effects on neurobehavioral functioning, including increased performance instability during tasks requiring sustained attention. The TOT effect is exacerbated by TSD, suggesting potentially overlapping mechanisms. We probed these mechanisms by investigating genotype-phenotype relationships on psychomotor vigilance test...

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Identifiers

PMID: 29029252
DOI: 10.1093/sleep/zsx167
PMCID: PMC5805243

Genes

COMT

Provenance

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