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Article

Dopamine transporter genotype predicts behavioural and neural measures of response inhibition.

Molecular psychiatry - 1 Nov 2012

Cummins T D R, Hawi Z, Hocking J, Strudwick M, Hester R, Garavan H, Wagner J, Chambers C D, Bellgrove M A

Abstract excerpt

The ability to inhibit unwanted actions is a heritable executive function that may confer risk to disorders such as attention deficit hyperactivity disorder (ADHD). Converging evidence from pharmacology and cognitive neuroscience suggests that response inhibition is instantiated within frontostriatal circuits of the brain with patterns of activity that are modulated by the catecholamines dopamine and...

Topics

Adult
Brain
Catecholamines
Dopamine Plasma Membrane Transport Proteins
Female
Functional Neuroimaging
Genetic Association Studies
Genotype
Humans
Inhibition, Psychological
Magnetic Resonance Imaging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Polymorphism, Single Nucleotide

Psychomotor Performance

Reaction Time

Source

Identifiers

PMID: 21876545
DOI: 10.1038/mp.2011.104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Response Inhibition and ADHD Traits: Correlates and Heritability in a Community SampleSemantic proximity Read ↗

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