Article
The potential association of tumor necrosis factor-βeta (252 G/A) cytokine gene polymorphism with immune thrombocytopenic purpura among Egyptian children.
Hematology (Amsterdam, Netherlands) - 1 Jun 2018
Morgan Dalia Saber, Afifi Rasha Abdel-RaoufAbdel-Aziz, El-Hoseiny Shereen Mohamed, Amin Dalia Gamil, Ibrahim Sara Yahia Gaber
Abstract excerpt
OBJECTIVES: The main objective of this study was to study tumor necrosis factor beta (TNFB) + 252G/A gene polymorphism, known to be related to autoimmunity, in immune thrombocytopenia (ITP) patients. We also aimed to investigate the association between TNFB + 252G/A polymorphism and susceptibility to develop persistent/chronic ITP. METHODS: One hundred pediatric ITP patients, as well as 50 age- and sex-matched...
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