Article
Single nucleotide polymorphisms of the inflammatory cytokine genes in adults with chronic immune thrombocytopenic purpura.
British journal of haematology - 1 Mar 2004
Satoh Takashi, Pandey Janardan P, Okazaki Yuka, Yasuoka Hidekata, Kawakami Yutaka, Ikeda Yasuo, Kuwana Masataka
Abstract excerpt
Single nucleotide polymorphisms (SNPs) of inflammatory cytokine genes were examined in 84 adult Japanese patients with chronic immune thrombocytopenic purpura (ITP) and 56 race-matched healthy controls. The SNPs examined were within the genes encoding tumour necrosis factor (TNF)-alpha (-238 G/A and -308 G/A), TNF-beta (+252 G/A), and interleukin (IL)-1beta (-511 C/T and +3953 T/C). Of these SNPs, the frequency...
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