Article
Association of TNF-α -308G>A and TNF-β +252A>G genes polymorphisms with primary immune thrombocytopenia: a North Indian study.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Oct 2016
Yadav Deependra K, Tripathi Anil K, Kumar Ashutosh, Agarwal Jyotsna, Prasad Kashi N, Gupta Divya, Singh Aloukick K
Abstract excerpt
Primary immune thrombocytopenia (ITP) is manifested by platelet autoantibodies that are not only responsible for platelet destruction by phagocytosis but also inhibit their production. Bleeding is the most common clinical manifestation of thrombocytopenia. ITP is a multifactorial disease in which both environmental and genetic factors have been implicated. It has been reported that several gene polymorphisms...
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