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Article

Impact of serum immunoglobulins level and IL-18 promoter gene polymorphism among Egyptian patients with idiopathic thrombocytopenic purpura.

Hematology (Amsterdam, Netherlands) - 1 Mar 2017

Aref Salah, El-Ghonemy Mohamed Sabry, El-Aziz Sherin Abd, Abouzeid Tarek, Talaab Mona, El-Sabbagh Amr

Abstract excerpt

OBJECTIVES: Based on the concept of immune dysregulation in immune thrombocytopenic purpura (ITP) and that Interleukin-18 (IL-18) is an inflammatory cytokine that plays an important role in autoimmune disease by inducing interferon-γ secretion; this study aimed to assess a possible association between the IL-18 promoter polymorphisms (-607 C/A site) and genetic susceptibility to ITP and the impact of the...

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Identifiers

PMID: 27600402
DOI: 10.1080/10245332.2016.1221213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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