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Article

Pattern of somatic mutations in patients with Waldenström macroglobulinemia or IgM monoclonal gammopathy of undetermined significance.

Haematologica - 1 Dec 2017

Varettoni Marzia, Zibellini Silvia, Defrancesco Irene, Ferretti Virginia Valeria, Rizzo Ettore, Malcovati Luca, Gallì Anna, Porta Matteo Giovanni Della, Boveri Emanuela, Arcaini Luca, Candido Chiara, Paulli Marco, Cazzola Mario

Abstract excerpt

We analyzed MYD88 and CXCR4 mutation status of 260 patients with Waldenström macroglobulinemia or IgM monoclonal gammopathy of undetermined significance using allele-specific real time quantitative polymerase chain reaction and Sanger sequencing, respectively. A subgroup of 119 patients was further studied with next-generation sequencing of 11 target genes (MYD88, CXCR4, ARID1A, KMT2D, NOTCH2, TP53, PRDM1, CD79B,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Monoclonal Gammopathy of Undetermined Significance

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Source

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Identifiers

PMID: 28983055
DOI: 10.3324/haematol.2017.172718
PMCID: PMC5709107

Genes

CXCR4
MYD88
NOTCH2
PRDM1
TNFAIP3
TRAF3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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