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Article

Base-resolution stratification of cancer mutations using functional variomics.

Nature protocols - 1 Nov 2017

Yi Song, Liu Ning-Ning, Hu Limei, Wang Hui, Sahni Nidhi

Abstract excerpt

A complete understanding of human cancer variants requires new methods to systematically and efficiently assess the functional effects of genomic mutations at a large scale. Here, we describe a set of tools to rapidly clone and stratify thousands of cancer mutations at base resolution. This protocol provides a massively parallel pipeline to achieve high stringency and throughput. The approach includes...

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Identifiers

PMID: 28981122
DOI: 10.1038/nprot.2017.086
PMCID: PMC6145840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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