Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeted deep resequencing of the human cancer genome using next-generation technologies.

Biotechnology & genetic engineering reviews - 1 Jan 2010

Myllykangas Samuel, Ji Hanlee P

Abstract excerpt

Next-generation sequencing technologies have revolutionized our ability to identify genetic variants, either germline or somatic point mutations, that occur in cancer. Parallelization and miniaturization of DNA sequencing enables massive data throughput and for the first time, large-scale, nucleotide resolution views of cancer genomes can be achieved. Systematic, large-scale sequencing surveys have revealed that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Neoplasm
Share to Genome, Human
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Neoplasms

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 21415896
DOI: 10.1080/02648725.2010.10648148
PMCID: PMC4340661

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeted deep resequencing of the human cancer genome using next-generation technologies.PMID 21415896Read ↗

Methods, challenges, and promise of next-generation sequencing in cancer biology.Semantic proximity Read ↗

Whole Cancer Genome Sequencing by Next-Generation MethodsSemantic proximity Read ↗

Advances in understanding cancer genomes through second-generation sequencing.Semantic proximity Read ↗

Comprehensive next-generation cancer genome sequencing in the era of targeted therapy and personalized oncologySemantic proximity Read ↗

Exploring the cancer genome in the era of next-generation sequencingSemantic proximity Read ↗

Application of second-generation sequencing to cancer genomics.Semantic proximity Read ↗

Unraveling the genetics of cancer: genome sequencing and beyond.Semantic proximity Read ↗

Next-Generation Sequencing for the Identification of Targetable Molecular Alterations in Cancer.Semantic proximity Read ↗

Genomic sequencing in cancer.Semantic proximity Read ↗

Deep sequencing in cancer research.Semantic proximity Read ↗

Clinical applications of next generation sequencing in cancer: from panels, to exomes, to genomesSemantic proximity Read ↗

New DNA sequencing technologies open a promising era for cancer research and treatment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.