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Article

Interplay between PTB and miR-1285 at the p53 3'UTR modulates the levels of p53 and its isoform Δ40p53α.

Nucleic acids research - 29 Sept 2017

Katoch Aanchal, George Biju, Iyyappan Amrutha, Khan Debjit, Das Saumitra

Abstract excerpt

p53 and its translational isoform Δ40p53 are involved in many important cellular functions like cell cycle, cell proliferation, differentiation and metabolism. Expression of both the isoforms can be regulated at different steps. In this study, we explored the role of 3'UTR in regulating the expression of these two translational isoforms. We report that the trans acting factor, Polypyrimidine Tract Binding protein...

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Identifiers

PMID: 28973454
DOI: 10.1093/nar/gkx630
PMCID: PMC5622325

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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