Article
Effect of a natural mutation in the 5' untranslated region on the translational control of p53 mRNA.
Oncogene - 29 Aug 2013
Khan D, Sharathchandra A, Ponnuswamy A, Grover R, Das S
Abstract excerpt
Tumor-suppressor protein p53, the 'guardian of the genome', is critical in maintaining cellular homeostasis and genomic stability. Earlier, we have reported the discovery of internal ribosome entry sites (IRESs) within the p53 mRNA that regulate the translation of the full length and its N-termin...
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