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Article

Influence of catechol-O-methyltransferase Val158Met on fear of pain and placebo analgesia.

Pain - 1 Jan 2018

Forsberg June T, Gjerstad Johannes, Flaten Magne Arve, Aslaksen Per M

Abstract excerpt

Higher levels of fear have been shown to partly explain individual differences in placebo analgesic responding. The catechol-O-methyltransferase (COMT) rs4680 Val158Met polymorphism has been associated with both increased placebo analgesia and increased fear-related behavior, in what appears to be inconsistent findings in the literature. The aim of the study was therefore to investigate placebo analgesia and...

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Source

Identifiers

PMID: 28968343
DOI: 10.1097/j.pain.0000000000001081

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Influence of catechol-O-methyltransferase Val158Met on fear of pain and placebo analgesia.PMID 28968343Read ↗

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