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Article

Evidence for a biopsychosocial influence on shoulder pain: pain catastrophizing and catechol-O-methyltransferase (COMT) diplotype predict clinical pain ratings.

Pain - 1 May 2008

George Steven Z, Wallace Margaret R, Wright Thomas W, Moser Michael W, Greenfield Warren H, Sack Brandon K, Herbstman Deborah M, Fillingim Roger B

Abstract excerpt

The experience of pain is believed to be influenced by social, cultural, environmental, psychological, and genetic factors. Despite this assertion, few studies have included clinically relevant pain phenotypes when investigating interactions among these variables. This study investigated whether psychological variables specific to fear-avoidance models and catechol-O-methyltransferase (COMT) genotype influenced...

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Source

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Identifiers

PMID: 17686583
DOI: 10.1016/j.pain.2007.06.019
PMCID: PMC2669670

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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