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Article

Effects of functional polymorphisms of opioid receptor mu 1 and catechol-O-methyltransferase on the neural processing of pain.

Psychiatry and clinical neurosciences - 1 May 2024

Cheong Yongjeon, Lee Seonkyoung, Okazawa Hidehiko, Kosaka Hirotaka, Jung Minyoung

Abstract excerpt

AIM: Pain is reconstructed by brain activities and its subjectivity comes from an interplay of multiple factors. The current study aims to understand the contribution of genetic factors to the neural processing of pain. Focusing on the single-nucleotide polymorphism (SNP) of opioid receptor mu 1 (OPRM1) A118G (rs1799971) and catechol-O-methyltransferase (COMT) val158met (rs4680), we investigated how the two pain...

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Source

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Identifiers

PMID: 38403942
DOI: 10.1111/pcn.13648
PMCID: PMC11488594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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