Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fear of pain moderates the relationship between self-reported fatigue and methionine allele of catechol-O-methyltransferase gene in patients with fibromyalgia.

PloS one - 1 Jan 2021

Ferrera David, Mercado Francisco, Peláez Irene, Martínez-Iñigo David, Fernandes-Magalhaes Roberto, Barjola Paloma, Écija Carmen, Díaz-Gil Gema, Gómez-Esquer Francisco

Abstract excerpt

Previous research has shown a consistent association among genetic factors, psychological symptoms and pain associated with fibromyalgia. However, how these symptoms interact to moderate genetic factors in fibromyalgia has rarely been studied to date. The present research investigates whether psychological symptoms can moderate the effects of catechol-O-methyltransferase on pain and fatigue. A total of 108 women...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fatigue

Share to Fibromyalgia

Share to Methionine

Share to Self Report

Source

Open in PubMed Open full text

Identifiers

PMID: 33909692
DOI: 10.1371/journal.pone.0250547
PMCID: PMC8081450

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fear of pain moderates the relationship between self-reported fatigue and methionine allele of catechol-O-methyltransferase gene in patients with fibromyalgia.PMID 33909692Read ↗

Psychological distress in fibromyalgia patients: a role for catechol-O-methyl-transferase Val158met polymorphism.Semantic proximity Read ↗

Association of polymorphism of the enzyme catechol-o-methyltransferase with fibromialgic syndrome and its clinical repercussionsSemantic proximity Read ↗

Catechol-O-methyltransferase Val158Met polymorphism influences anxiety, depression, and disability, but not pressure pain sensitivity, in women with fibromyalgia syndrome.Semantic proximity Read ↗

Influence of catechol-O-methyltransferase (COMT) gene polymorphisms in pain sensibility of Brazilian fibromialgia patients.Semantic proximity Read ↗

Pain sensitivity in fibromyalgia is associated with catechol-O-methyltransferase (COMT) gene.Semantic proximity Read ↗

Association between catechol-O-methyl transferase gene polymorphisms and fibromyalgia in a Korean population: A case-control study.Semantic proximity Read ↗

Association between the COMT Val158Met polymorphism and fibromyalgia susceptibility and fibromyalgia impact questionnaire score: a meta-analysis.Semantic proximity Read ↗

COMT moderates the relation of daily maladaptive coping and pain in fibromyalgia.Semantic proximity Read ↗

UNRAVELING THE CLINICO-GENETIC ASSOCIATION OF CATECHOL-O-METHYLTRANSFERASE-RS4680 G>A GENE POLYMORPHISM IN WOMEN WITH FIBROMYALGIA SYNDROME.Semantic proximity Read ↗

The relationship between a common catechol-O-methyltransferase (COMT) polymorphism val(158) met and fibromyalgia.Semantic proximity Read ↗

Genetic and epigenetic regulation of Catechol-O-methyltransferase in relation to inflammation in chronic fatigue syndrome and Fibromyalgia.Semantic proximity Read ↗

The polymorphism Val158Met in the COMT gene: disrupted dopamine system in fibromyalgia patients?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.