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Article

Genome-wide linkage and association analysis of primary open-angle glaucoma endophenotypes in the Norfolk Island isolate.

Molecular vision - 1 Jan 2017

Matovinovic Elizabeth, Kho Pik Fang, Lea Rodney A, Benton Miles C, Eccles David A, Haupt Larisa M, Hewitt Alex W, Sherwin Justin C, Mackey David A, Griffiths Lyn R

Abstract excerpt

PURPOSE: Primary open-angle glaucoma (POAG) refers to a group of heterogeneous diseases involving optic nerve damage. Two well-established risk factors for POAG are elevated intraocular pressure (IOP) and a thinner central corneal thickness (CCT). These endophenotypes exhibit a high degree of heritability across populations. Large-scale genome-wide association studies (GWASs) of outbred populations have robustly...

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Source

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Identifiers

PMID: 28966548
PMCID: PMC5620381

Genes

DLG2
BANP
RAPSN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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