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GWAS for primary angle-closure glaucoma identifies loci related to ocular biometry and morphology

14 Nov 2025

Abstract excerpt

GWAS of primary angle-closure glaucoma have identified eight loci conferring risk in Asian populations. However, it remains unclear whether the genetic risk factors for the disease are consistent across different populations. Here, we present a discovery GWAS for primary angle-closure glaucoma in Europeans using the UK Biobank. We replicate our findings in six independent European populations and compare these...

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PMID: 41238566
DOI: 10.1038/s41467-025-64949-z

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