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Article

Influence of polygenic risk scores on lipid levels and dyslipidemia in a psychiatric population receiving weight gain-inducing psychotropic drugs.

Pharmacogenetics and genomics - 1 Dec 2017

Delacrétaz Aurélie, Lagares Santos Patricia, Saigi Morgui Nuria, Vandenberghe Frederik, Glatard Anaïs, Gholam-Rezaee Mehdi, von Gunten Armin, Conus Philippe, Eap Chin B

Abstract excerpt

OBJECTIVES: Dyslipidemia represents a major health issue in psychiatry. We determined whether weighted polygenic risk scores (wPRSs) combining multiple single-nucleotide polymorphisms (SNPs) associated with lipid levels in the general population are associated with lipid levels [high-density lipoprotein (HDL), low-density lipoprotein (LDL), total cholesterol (TC), and triglycerides] and/or dyslipidemia in...

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Identifiers

PMID: 28945215
DOI: 10.1097/FPC.0000000000000313

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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