Article
Association of genetic risk scores with body mass index in Swiss psychiatric cohorts.
Pharmacogenetics and genomics - 1 May 2016
Saigi-Morgui Núria, Vandenberghe Frederik, Delacrétaz Aurélie, Quteineh Lina, Gholamrezaee Mehdi, Aubry Jean-Michel, von Gunten Armin, Kutalik Zoltán, Conus Philippe, Eap Chin B
Abstract excerpt
OBJECTIVE: Weight gain is associated with psychiatric disorders and/or with psychotropic drug treatments. We analyzed in three psychiatric cohorts under psychotropic treatment the association of weighted genetic risk scores (w-GRSs) with BMI by integrating BMI-related polymorphisms from the candidate-gene approach and Genome-Wide Association Studies (GWAS). MATERIALS AND METHODS: w-GRS of 32 polymorphisms...
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