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Article

Polygenic risk scores enhance prediction of body mass index increase in individuals with a first episode of psychosis

1 Jan 2023

Abstract excerpt

BACKGROUND: Individuals with a first episode of psychosis (FEP) show rapid weight gain during the first months of treatment, which is associated with a reduction in general physical health. Although genetics is assumed to be a significant contributor to weight gain, its exact role is unknown. METHODS: = 157) set to calculate the polygenic risk score (PRS) in a two-step process. In parallel, we obtained reference...

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PMID: 36852609
DOI: 10.1192/j.eurpsy.2023.9

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